Pentobarbital will decrease the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. Older adults or those with chronic medical conditions may experience depression, confusion, or excitement after taking the drug. pentobarbital will decrease the level or effect of bexarotene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. https://bookmarkassist.com/story20197807/un-imparziale-vista-pentobarbital-hond