Conolidine’s analgesic consequences stem from its conversation with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors inside the central anxious process, conolidine modulates alternate molecular targets. A Science Advancements examine observed that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availa... https://conolidintoreplacetraditi27047.luwebs.com/40011608/conoldine-alternative-natural-pain-relief-an-overview